IPHRC Projects

IPHRC investigators and co-investigators are involved in a variety of projects focused on maternal and neonatal health.


PROMPT: Predicting Maturity, Mortality and Morbidity in Preterm Newborns

The PROMPT study is a multi-site study funded by the National Institute of Child Health and Development (NICHD R01 HD102381). The study includes both retrospective and prospective data from the University of California San Francisco and the University of Iowa on preterm newborns <32 weeks gestation. PROMPT examines metabolic biomarkers measured as part of routine newborn screening for prediction of the risk of neonatal morbidity and in-hospital mortality.


PREMISE: Preterm Research on Epigenetics, Metabolites, Infant development, Stress and Environment

The goal of PREMISE is to identify biological (e.g., epigenetics, metabolite vulnerability profiles) and environmental (e.g., parental stress, parent-child interactions) factors that relate to neurodevelopmental outcomes in preterm-born infants. The proposed research is to longitudinally examine interactions between epigenetics, metabolites, stress, environment, and language development. At five different time points (around every six months), parents will complete a set of online questionnaires, and parents and infants will complete various interactive activities together. At two of those time points (at the one and two-year marks), infants will undergo a multi-method, multi-informant assessment, which primarily includes an examination of neurocognitive abilities.

HOPE logo

HOPE Consortium: Healthy Outcomes of Pregnancy for Everyone through Science, Partnership, and Equity

The HOPE Consortium brings together academic, public health and community partners to look at risk and resiliency for adverse pregnancy and infant outcomes. This research focuses on the contribution of molecular, family, community, and societal factors to adverse pregnancy and infant outcomes. The HOPE Consortium is especially focused on women, birthing persons, and infants at the highest risk including those who are Black and Brown and those living in poverty or whom have a mental illness or disability.

Perinatal Connect logo

Perinatal Connect

The mission of Perinatal Connect is to improve maternal health through early identification of risk factors during pregnancy and the postpartum period. Their research focuses on identifying major risk factors associated with depressive disorders for women. They are particularly interested in collaborative care approaches for identifying and assessing depressive symptoms in health care settings to improve health outcomes for women over the life course.

IMQCC logo

The Iowa Maternal Quality Care Collaborative (IMQCC)

The IMQCC is a multi-disciplinary task force that serves as the principal oversight body responsible for improving communication and collaboration among groups addressing obstetrical care in Iowa.